Tan Ying
Associate Professor

Professional Experience & Education

Professional History:
    Oct 2012-present, Lecturer and Associate Professor, Graduate School at Shenzhen,Tsinghua University

    Oct 2016-Oct 2017, Visiting Scholar, National University of Singapore

    Jul 2010-Jul 2012, Postdoctoral Fellow, Guangdong Provincial Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University

Education:

    2005-2010, Ph.D. in chemical biology, Central China Normal University

    2001-2005, B.S. in applied chemistry, Central China Normal University


Instruction & Advising

Current Courses:

    Analytical Chemistry for Life Science

    Modern Instrumental Analysis

Master's & Ph.D. Advising:

    Molecular biology

    Cytobiology

    Organic chemistry


Research Interests:

    Interaction between biomacromolecule and small molecules;

    Fluorescence-based biosensors using conjugated polyelectrolytes and molecular probes targeting cancer diagnosis and drug mechanism studies;

    Computational biology including bioinformatics, biomarker discovery, immunology



[1]      Zhiqiang Xu, Xiaoting Huang, Xie Han, Di Wu, Bibo Zhang, Ying Tan*, Meijiao Cao, Sheng Hua Liu, Jun Yin*, Juyoung Yoon*. A Visible Near-Infrared, Dual Channel Fluorescence-On Probe for Highly Selective Tracking of Mitochondrial Glutathione. Chem. 4, 1609-1628, 2018. 

[2]      Shuwen Liu, Naihan Xu, Chunyan Tan, Wei Fang, Ying Tan*, Yuyang Jiang. A sensitive colorimetric aptasensor based on trivalent peroxidasemimic DNAzyme and magnetic nanoparticles. Analytica Chimica Acta. 1018, 86-93, 2018.

[3]      Wei Fang, Shuwen Liu, Chunyan Tan,* Anqi Li, Ying Tan* and Yuyang Jiang. Conjugated polyelectrolytes with a label-free aptamer for specific protein photoinactivation. Analytical Methods, 10, 2205-2210, 2018. (cover page)

[4]      Rui Yang, Shuwen Liu, Zhenjie Wu, Ying Tan*, Shuqing Sun*. Core-shell assay based aptasensor for sensitive and selective thrombin detection using dark-field microscopy. Talanta, 182, 348–353, 2018.

[5]      Huan Shi, Bibo Zhang, Shuwen Liu, Chunyan Tan, Ying Tan,* and Yuyang Jiang. A New Strategy Involving the Use of Peptides and Graphene Oxide for Fluorescence Turn-on Detection of Proteins. Sensors, 18, 385, 2018.

[6]      Xiaoting Huang, Haiyang Liu, Wei Fang, Yan Lin,* and Ying Tan,* Sensitive and Selective Immunofluorescence Assay for CA15-3 Detection Using Fluorescein Derivative A10254. Protein & Peptide Letters, 25, 1-7, 2018.

[7]      Wei Zhang, Cunlong Zhang, Feng Liu, Yu Mao, Wei Xu, Tingting Fan, Qinsheng Sun, Shengnan He, Yuzong Chen, Wei Guo*, Ying Tan*, and Yuyang Jiang*. Antiproliferative activities of the second-generation antipsychotic drug sertindole against breast cancers with a potential application for treatment of breast-to-brain metastases. Scientific reports. 2018, Accepted.

[8]      Kai Cai1, Ying Tan1, Chunyan Tan,* Jiatao Wu, Pan Wu, Jiamei Liang, Shuwen Liu, Bibo Zhang and Yuyang Jiang. An iminodiacetate-modified conjugated polyelectrolyte for fluorescent labeling of histidine-tagged proteins. Chemical Communication. 53(30): 4191-4194, 2017. (These authors contributed equally to this work)

[9]      Zhiqiang Xu, Jianhua Chen, Lin-Li Hua,* Ying Tan,* Sheng-Hua Liu, Jun Yin*. Recent advances in formaldehyde-responsive fluorescent probes. Chinese Chemical Letters. 28, 1935-1942, 2017.

[10]  Xie Han, Bibo Zhang, Jianhua Chen, Sheng Hua Liu, Chunyan Tan, Haiyang Liu, Matthew J. Lang, Ying Tan,* Xiaogang Liu * and Jun Yin*. Modulating aggregation-induced emission via a non-conjugated linkage of fluorophores to tetraphenylethenes. Journal of Materials Chemistry B, 5, 5096-5100, 2017.

[11]  Pengcheng Xue, Shengnan He, Yu Mao, Long Qu, Feng Liu, Chunyan Tan, Yuyang Jiang, Ying Tan*. The Optimization and Characterization of an RNA-cleaving Fluorogenic DNAzyme Probe for MDA-MB-231 Cell Detection. Sensors, 17(3): 650, 2017.

[12]  Bibo Zhang, Haiyang Liu, Fengxu Wu, Gefei Hao, Yuzong Chen, Chunyan Tan*, Ying Tan*, Yuyang Jiang. A dual-response quinoline-based fluorescent sensor for the detection of Copper (II) and Iron (III) ions in aqueous medium. Sensors and Actuators B: Chemical. 243, 765-774, 2017.

[13]  Yu Liu, Pan Wu, Jianhua Jiang, Jiatao Wu, Yan Chen, Ying Tan*, Chunyan Tan*, and Yuyang Jiang. Conjugated Polyelectrolyte Nanoparticles for Apoptotic Cell Imaging. ACS Applied Materials & Interfaces. 8 (34), 21984–21989, 2016.

[14]  Haiyang Liu, Bibo Zhanga, Chunyan Tana, Feng Liu, Jiakun Cao, Ying Tan* and Yuyang Jiang*. Simultaneous bioimaging recognition of Al3+ and Cu2+ in living-cell, and further detection of F? and S2? by a simple fluorogenic benzimidazole-based chemosensor. Talanta. 161:309-319, 2016.

[15]  Haiyang Liu, Fengxu Wu, Bibo Zhang, Chunyan Tan, Yuzong Chen, Gefei Hao, Ying Tan* and Yuyang Jiang*. A simple quinoline-derived fluorescent sensor for the selective and sequential detection of copper (II) and sulfide ions and its application in living-cell imaging. RSC Advance, 6, 77508-77514, 2016.

[16]  Chen, Z.; Wu, P.; Cong, R.; Xu, N.; Tan, Y.*; Tan, C*.; Jiang, Y., Sensitive Conjugated-Polymer- Based Fluorescent ATP Probes and Their Application in Cell Imaging. ACS Applied Materials & Interfaces. 8, 3567-3574, 2016.

[17]  Haiyang Liu, Yunsheng Dong, Bibo Zhang, Feng Liua, Chunyan Tana, Ying Tan*, Yuyang Jiang. An efficient quinoline-based fluorescence sensor for zinc (II) and itsapplication in live-cell imaging. Sensors and Actuators B: Chemical. 234, 616–624, 2016.

[18]  Ying Lv, Jiatao Wu, Pan Wu, Yu Zong Chen, Ying Tan,* Chunyan Tan* and Yuyang Jiang. A sensitive polymeric dark quencher-based sensing platform for fluorescence “turn on” detection of proteins. RSC Advance, 6, 42443–42446, 2016.

[19]  Zheng Jing, Tan Chunyan, Xue Pengcheng, Cao Jiakun, Liu Feng, Tan Ying*, Jiang Yuyang, Proteolysis targeting peptide (PROTAP) strategy for protein ubiquitination and degradation. Biochemical and Biophysical Research Communications. 470(4): 936-940, 2016.

[20]  Jiatao Wu, Chunyan Tan,* Zhifang Chen, Yu Zong Chen, Ying Tan* and Yuyang Jiang. Fluorescence array-based sensing of nitroaromatics using conjugated polyelectrolytes. Analyst. 141, 3242–3245, 2016. Changjun Chen, Haiyang Liu, Bin Zhang, Yanwei Wang, Kai Cai, Ying Tan*, Chunmei Gao*, Hongxia Liu, Chunyan Tan, Yuyang Jiang. A simple benzimidazole quinoline-conjugate fluorescent chemosensor for highly selective detection of Ag+. Tetrahedron. 72, 3980-3985, 2016.