Liu Feng
Assistant Professor

Professional Experience & Education

Professional History

        2011-present, Assistant Professor, Graduate School at Shenzhen, Tsinghua University

        2008-2010, Postdoctoral Fellow, Graduate School at Shenzhen, Tsinghua University

Education

        2004-2008, Ph.D., Tsinghua University

        2001-2004, M.S., Henan University of Technology

        1997-2001, B.S., Henan University of Technology


Instruction & Advising

        Current Courses: Modern Life Science and Biotechnology Experiments

        Master's & Ph.D. Advising: Tumor Chemical Biology


Research Interests:

  • Nucleic acid molecular probes for the detection of tumor-associated molecules;

  • Analysis and detection of tumor biomarkers;

  • Study on mechanism of anticancer drug lead compounds


[1]           Jingxian Yin, Feng Liu*, Tingting Fan, Yue Ren, Yuyang Jiang. Rapid detection of methyltransferases utilizing dumbbell DNA-templated copper nanoparticles, Sensors & Actuators: B. Chemical, 2018, 276, 499–506

[2]           Wenlu Li, Qinsheng Sun, Lu Song, Chunmei Gao, Feng Liu*,Yuzong Chen, Yuyang Jiang*. Discovery of 1-(3-aryl-4-chlorophenyl)-3-(p-aryl)urea derivatives against breast cancer by inhibiting PI3K/Akt/mTOR and Hedgehog signalings, European Journal of Medicinal Chemistry, 2017,141,721-733

[3]           Tingting Fan, Yu Mao, Feng Liu, Wei Zhang, Jingxian Yin, Yuyang Jiang. Dual signal amplification strategy for specific detection of CirculatingmicroRNAs based on Thioflavin T, Sensors and Actuators B, 2017, 249, 1–7

[4]           Yu Mao, Tingting Fan, Rachel Gysbers, Yin Tan, Feng Liu, Shuo Lin, Yuyang Jiang. A simple and sensitive aptasensor for colorimetric detection of adenosine triphosphate based on unmodified gold nanoparticles, Talanta, 2017,168, 279–285

[5]           Shengnan He, Long Qu, Ying Tan, Feng Liu, Yu Wang, Wei Zhang, Zhiming Cai, Lisha Mou and Yuyang Jiang. A fluorescent aptasensor with product-triggered amplification by exonuclease III digestion for highly sensitive ATP detection, Analytical Methods, 2017, 9, 4837–4842

[6]           Wanxiang Shen, Tao Xiao, Shangying Chen, Feng Liu, Yu Zong Chen, and Yuyang Jiang*. Predicting the Enzymatic Hydrolysis Half-lives of New Chemicals Using Support Vector Regression Models Based on Stepwise Feature Elimination, Molecular Informatics, 2017,36, 1600153

[7]           Haiyang Liu, Yunsheng Dong, Bibo Zhang, Feng Liu, Chunyan Tan, Ying Tan, Yuyang Jiang. An efficient quinoline-based fluorescence sensor for zinc(II) and its application in live-cell imaging, Sensors and Actuators B-Chemical, 2016,234,616-624

[8]           Shengnan He, Long Qu, Zhifa Shen, Ying Tan, Meiyun Zeng, Feng Liu*, Yuyang Jiang*, Yingfu Li, Highly Specific Recognition of Breast Tumors by an RNA-Cleaving Fluorogenic DNAzyme Probe. Analytical Chemistry, 2015,87(1):569-577.

[9]           Bizhu Chu, Feng Liu*, Lu-lu Li, Chao Ding, Kang Chen, Qin-sheng Sun, Zhifa Shen, Ying Tan, Chunyan Tan, Yuyang Jiang*, A benzimidazole derivative exhibiting antitumor activity blocks EGFR and HER2 activity and upregulates DR5 in breast cancer cells. Cell Death & Disease, 2015,6, e1686.

[10]       Kang Chen, Bizhu Chu, Feng Liu*, Bin Li, Chun-mei Gao, Lu-lu Li, Qin-sheng Sun, Zhifa Shen, Yuyang Jiang*, New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway. Acta Pharmacological Sinica, 2015,36(9):1074-1084.

[11]       Fei Gao, Feng Liu*, Jing Zheng, MeiYun Zeng, Yuyang Jiang*, A Catalytic DNA Probe with Stem-loop Motif for Human T47D Breast Cancer Cells. Analytical Sciences, 2015,31(8):815-822.

[12]       Chunmei Gao*, Wei Zhang, Shengnan He, Shangfu Li, Feng Liu*, Yuyang Jiang, Synthesis and antiproliferative activity of 2,7-diamino l0-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as potent telomeric G-quadruplex DNA ligands. Bioorganic Chemistry, 2015,60,30-36.

[13]       Haiyang Liu, Xiaoshuang Li, Feng Liu, Ying Tan*, Yuyang Jiang. A simple and novel amide ligand based on quinoline derivative used for palladium-catalyzed Suzuki coupling reaction, Journal of Organometallic Chemistry, 2015, 794, 27-32

[14]       Zhe Chen, Feng Liu,* Nannan Zhang, Shiying Liu, Yuyang Jiang. p38β, A Novel Regulatory Target of Pokemon in Hepatic Cells, International Journal of Molecular Sciences, 2013,14, 13511-13524

[15]       Xiuli Jin, Qinsheng Sun, Feng Liu, Hongwei Yang, Min Liu, Hongxia Liu, Wei Xu, Yuyang Jiang. microRNA 21-mediated suppression of Sprouty1 by Pokemon affects liver cancer cell growth and proliferation, Journal of Cellular Biochemistry,2013,7,1625-1633

Kun Liu, Feng Liu*, Nannan Zhang, Shiying Liu, Yuyang Jiang. Pokemon Silencing Leads to Bim-Mediated Anoikis of Human Hepatoma Cell QGY7703, International Journal of Molecular Sciences, 2012, 13, 5818-5831.