Ma Lan
Professor

Professional Experience & Education

Professional History:

    2014-present, Associate Dean, Graduate School at Shenzhen, Tsinghua University

    2013-2014, Director, Research Office, Graduate School at Shenzhen, Tsinghua University

    2012-present, Laboratory Chief, Shenzhen Innovative Nano-Diagnostic Reagents Engineering Laboratory

    2011- present, Professor, Graduate School at Shenzhen, Tsinghua University

    2005-2011, Associate professor, Graduate School at Shenzhen, Tsinghua University

    2000-2005, Associate Professor, School of Life Sciences, Yunnan University

    1997-1998, Visiting Scholar, Wisconsin National Primate Research Center, University of Wisconsin-Madison

    1995-2000,  Lecturer, School of Life Sciences, Yunnan University

    1993-1995, Teaching Assistant, School of Life Sciences, Yunnan University

    1987-1990, Assistant Scientist, Kunming Institute of Zoology, The Chinese Academy of Sciences

Education:

    Ph.D. in Stem Cell Biology, August 2003, University of Chinese Academy of Sciences, Beijing, China

    M.S. in Immunology, June 1993, Peking University, Beijing, China

    B.S. in Genetics, July 1987, Wuhan University, Wuhan, China


Current Courses:

  • Molecular Immunology

  • Modern Life Science & Biotechnology

  • Cancer Diagnostics and Nanomedicine


Research Interests:

  • Stem cell biology;

  • Nano-biomedicine;

  • Vaccine & antibody bio-engineering


Research Projects:

    [1] "Integrated study of quantum dot-based nano-material and its application for diagnosis of major diseases,"  Hi-Tech Research and Development Program of China, From Sep. 2013 to Sep. 2016.

    [2] "Shenzhen innovative nano-diagnostic reagents engineering laboratory,"  Shenzhen Development and Reform Commission Grant, from Dec. 2012 to Dec. 2014.

    [3] "Development of sensitive distinguishable POCT reagents for the detection of influenza A (H1N1) virus,"  Guangdong Science and Technology Council Grant, from Oct. 2012 to Sep. 2014.

    [4] "Development of a fluorescent quantum dots-based sensitive reagent for rapid quantitative detection of procalcitonin (PCT),"  Shenzhen Science and Technology Innovation Council Grant, from Jan. 2013 to Jan. 2014.

    [5] "Development of the fluorescent immuno-reagent for early detection of gastric cancer,"  Shenzhen Science and Technology Innovation Council Grant, from Aug. 2014 to Aug. 2016.

    [6] "Research & Development of sensitive POCT immunoassay kits for the detection of highly pathogenic avian influenza virus," Shenzhen Science and Technology Innovation Council Grant, from Oct. 2014 to Oct. 2016.


Additional Positions:

2007-present, Member, Nano Science and Technology Branch of Chinese Society of Micro-Nano Technology

2014-present, Vice president, Shenzhen Life Science and Biotechnology Association

2014-present, Full affiliate member,Houston Methodist Research Institute (HMRI)


[1] Feng Wu,  Mao Mao,  Yu Cen,  Hongtian Yang,  Zhifeng Qin  and  Lan Ma*. Copolymerization of Eu(TTA)3Phen doped styrene and methyl methacrylate nanoparticles and use in quantitative detection of pepsinogen. RSC Adv., 2017,7:12217-12223.

[2] Yiwei Shu, Ho Nam Chan, Dongshi Guan, Hongkai Wu*, Lan M*.A simple fabricated thickness-based stiffness gradient for cell studies. Science Bulletin., 2017, 62(3): 222-228.

[3] Feng Wu, Hang Yuan, Changhua Zhou, Mao Mao, Qian Liu, Huaibin Shen, Yu Cen, Zhifeng Qin, Ling Song Li* , Lan Ma*. Multiplexed detection of influenza A virus subtype H5 and H9 via quantum DoT-based immunoassay. Biosensors and Bioelectronic,, Biosensors and Bioelectronics., 2016, 77: 464-470.

[4] Wenxiu Zhao, Lei Jin, Hang Yuan, Zhiyang Tan, Changhua Zhou, Lin Song Li*& Lan Ma*. Targeting human embryonic stem cells with quantum dot-conjugated phages. Scientific Reports., 2013, 3 : 3134.

[5] Changhua Zhou, Mao Mao, Hang Yuan, HuaibinShen, FengWu ,Lan Ma* , Lin Song Li*. Fluorescent QDs-polystyrene composite nanospheres for highly efficient and rapid protein antigen detection. J Nanopart Res., 2013, 15:1901.

[6] Zhou Changhua; Yuan Hang; Wang Xin; Shen Huaibin; Guo Yi; Xu Li; Wu Feng; Ma Lan*; LiLin Song*. CdSe/ZnS Quantum Dots with Multi-Shell Protection: Synthesis and Application in the Detection of Ractopamine Residue in Swine Urine, Science of Advanced Materials., 2013, 5(3):285-294.

[7] Sujuan Wang; Changhua Zhou; Hang Yuan; Huaibin Shen; Wenxiu Zhao; Lan Ma*; Lin Song Li*. A robust ligand exchange approach for preparing hydrophilic, biocompatible photoluminescent quantum dots. Materials Research Bulletin., 2013, 48:2836-2842.

[8] Dan Liu, Feng Wu, Changhua Zhou, Huaibing Shen, Hang Yuan, Zuliang Du, Lan Ma?, Lin Song Li?. Multiplexed immunoassay biosensor for the detection of serum biomarkers -β-HCG and AFP of Down Syndrome based on photo luminescent water-soluble CdSe/ZnS quantum dots, Sensors and Actuators B., 2013, 186:235-243.

[9] Weiwei Xu, Jinzhong Niu, Hangying  Shang, Huaibin Shen*, Lan Ma*, Lin Song Li. Facile synthesis of AgAu alloy and core/shell nanocrystalsby using Ag nanocrystals as seeds, Gold Bull., 2013, 46:19-23.

[10] WenxiuZhao , Xiang Ji , Fangfang Zhang , Liang Li  and Lan Ma*. Embryonic Stem Cell Markers. Molecules., 2012, 17, 6196-6236.

[11] Huaibin Shen, Hang Yuan, Feng Wu, Xianwei Bai, Changhua Zhou, Hongzhe Wang, Tikang Lu, Zhifeng Qin,  Lan Ma* and Lin Song Li*. Facile synthesis of high-quality CuInZnxS2+x core/shell nanocrystals and their application for detection of C-reactive protein. J. Mater. Chem., 2012, 22, 18623-18630.

[12] Huaibin Shen,Hongzhe,Wang,Hang Yuan, Lan Ma* and Lin Song Li*. Size-, shape-, and assembly-controlled synthesis of Cu2xSe nanocrystals via a non-injection phosphine-free colloidal method.  CrystEngComm., 2012, 14, 555-560.

[13] WeiweiXu, Huaibin Shen, Jin Zhong Niu, Changhua Zhou, Cailan Yu,Xiaomin Li, Yuan Hang, Hongzhe Wang, Lan Ma* and Lin Song Li*. Facile synthesis and observation of discontinuous red-shift photoluminescence of CdTe/CdS core/shell nanocrystals. CrystEngComm., 2012, 14, 272-277.

[14] Xu, Shasha; Shen, Huaibin; Zhou, Changhua; Hang, Yuan; Liu, Changsong; Wang, Hongzhe; Ma, Lan*, Li, Lin Song*. Effect of Shell Thickness on the Optical Properties in CdSe/CdS/Zn0.5Cd0.5S/ZnS and CdSe/CdS/ZnxCd1-xS/ZnS Core/Multishell Nanocrystals. J. Phys. Chem. C., 2011, 115, 20876-20881.

[15] Changhua Zhou,Hang Yuan, Huaibin Shen, Yi Guo, Xiaomin Li, Dan Liu, Li Xu, Lan Ma* and Lin Song Li*. Synthesis of size-tunable photoluminescent aqueous CdSe/ZnS microspheres via a phase transfer method with amphiphilic oligomer and their application for detection of HCG antigen, J. Mater. Chem., 2011, 21, 7393-7400.

[16] Huaibin Shen, HongzheWangChanghuaZhou,Jin Zhong Niu, Hang Yuan, Lan Ma* and Lin Song Li*. Large scale synthesis of stable tricolor Zn1 - xCdxSe core/multishell nanocrystals via a facile phosphine-free  colloidal method, Dalton Trans., 2011, 40, 9180-9188.

[17] Huaibin Shen, HangYuan, Jin Zhong Niu, Shasha Xu, ChanghuaZhou, LanMa* and Lin Song Li*. Phosphine-free synthesis of high-quality reverse type-I ZnSe/CdSe core with CdS/CdxZn1?xS/ZnS multishell nanocrystals and their application for detection of human hepatitis B surface antigen, Nanotechnology., 2011,22, 375602 (10pp).

[18] Xiaomin Li, Honglei Si, Jinzhong Niu, Huaibin Shen, Changhua Zhou, Hang Yuan, Hongzhe Wang, Lan Ma* and Lin Song Li*. Size-controlled syntheses and hydrophilic surface modification of Fe3O4, Ag, and Fe3O4/Ag heterodimer nanocrystals,Dalton Trans., 2010, 39, 10984-10989.


2006   China Standard Innovation Award,Standardization Administration of China

2004   National innovation expert, China Federation of Trade Unions

2003   2003 'China Economic Women of the Year', China Women's Federation

2002   New century women's outstanding inventor, China Women's Federation and China Intellectual Property Office

2002   National "three eight" red banner pacesetter, China Women's Federation